The building here was mentioned in a registered document for the first time in 1406. It was noted as formerly having been Niklas of Valich’s property, yet the owner had already passed away at the time of the chronicle entry. The building’s next entrance into written documentation was in 1566. During this area, a cobbler named Hans Präntlin was the owner. It was also during his ownership that it came to be known as the "House of the Golden Dragon". The story behind this particular name eventually has gotten lost over the ages, but the symbol for the building - the golden dragon - is still displayed above the entranceway today.

The next period of this building's diverse history begins at the end of the second Turkish invasion. Johann Steindl, inner city council and hospital director, had been so valiant in defending the city of Vienna during the invasion that the building was signed over to him in gratitude for his efforts in 1683. From this time on, it was also known as the "Steindl House". Johann Steindl converted the house into an inn that has been in service as such since then, making it one of Vienna's oldest inns.

In 1700, the inn was taken over by the Kaiser's imperial city and regional court director, Johann Stephan Grundl, who signed it over to the Mauerbach Monastery in twenty-five years later. In 1770, the building changed hands again when Georg Strohmeyer became the owner. The inn then repeatedly changed ownership: the City of Vienna became the owner in 1784, Mathias Reiterer in 1790, Barbara Schmiedel in 1830, Josef Zwickhl's heirs in 1849, and Anton Polan in 1896.

Since 1924, the building has been in possession of the Gösser Brewery Ltd.

In 1926, it was leased to Hans Stiedl. Two generations of the Stiedl family managed the inn until 1987.

In 1988, Hieronymus Kos took over the inn. After meticulous and careful renovation he was able to recapture the style of the traditional Gösser Brewery.

In the summer of 2000, the Gösser Bierklinik was improved, remodeled and restored in order to regain its magical atmosphere and its historical architectural design. The rooms inside were enlarged to form one large space, which was opened to include the covered courtyard where you can now enjoy your beer "outside" without having to worry about the weather. This has been made possible through the installation of a high-tech computer-controlled device that regulates the atmosphere (through lighting) within the courtyard area. The sandstone stairway takes you up to the "Steindlzimmer" ("Steindl Room"), a dining space that resembles the inn atmosphere from 1683. This area also includes two balconies with a view overlooking the courtyard.